The Sezary Syndrome: A Rare case of Cutaneous T cell Lymphoma

Authors: Singh R*, Billawaria S, Tahsildar M and Desai N

DOI: 10.23880/cprj-16000191

Volume 8, Issue 1

Abstract

Sezary syndrome is uncommon variant of cutaneous T-cell lymphoma (CTCL) characterized by erythroderma, pruritus and atypical lymphocytes with cerebriform nuclei. Hereby, the authors present a rare case of 60 years male with multiple hyperpigmented scaly plaques over face, bilateral upper, lower limbs, abdomen and trunk since 6 months. On Peripheral smear examination revealed Sezary cells of intermediate to large size with cerebriform nuclei with scant blue cytoplasm. Skin biopsy of the patient revealed atypical lymphoid infiltrate in the superficial dermis characterized by small cells with irregular nuclear contour and hyperchromatic chromatin (Sezary Cells). Hence there is a need for skin biopsies in patients with erythrodermic lesion with suspicion for Cutaneous T cell Lymphoma.

Keywords: Sezary Syndrome; Cutaneous T-Cell Lymphoma; Mycosis Fungoides; Peripheral Smear

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